The fecal transplantation process usually starts by locating a donor. This donor should have a healthy digestive system with no known digestive problems. Often someone from the same family is recommended. Some people have had their spouse provide the donated fecal matter. In a clinical setting usually tests are run to verify the donor has a healthy digestive system that is clear of viruses, bacteria or parasites that could be harmful. People who do not have access to a clinic willing to do fecal transplantation have just taken the donor’s healthy digestive system history as enough evidence to continue.

In order to provide a steady, daily supply of fecal matter, the donor should eat a fiber rich diet. Usually the recipient is put on a low fiber diet & then eventually a liquid diet right before the transplantation occurs. In a clinical setting the recipient may be given a course of antibiotic drugs & then a powerful laxative, essentially the same stuff you’d get during colonoscopy preparations. Again, people who are doing fecal transplantation on their own have skipped these steps.

The fecal matter must be fresh & used immediately. Once the fecal matter has been “donated” into a disposable container it is then placed into a blender & mixed throughly with a salt water solution. Salt water is less irritating than regular water to the mucous membrane within the lower digestive system. In a clinical setting this slurry is then filtered or strained so that it be used more easily as an enema or in some cases via a naso-gastric tube. After the recipient has received the fecal transplant they may be given anti-diarrheal medication like Loperamide to prevent cramping. This process is then repeated for approximately 5 – 10 days.